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Post by Dianna on Mar 16, 2017 17:47:48 GMT -5
well, I have heard more positive things about Kratom than negative. Everyone reacts differently. When I first tried Kratom I mixed it with orange juice (I don't like tea), and it was just gross and made me throw up. .Big Mistake LOL Then I used capsules which worked better for me. I have chronic muscle spasms and pain, and now lower back pain. Not a fan of painkillers so I researched Kratom and by asking others.. I prefer natural vs rx's . I did try Marijuana but it has horrible effects on me and makes me sick... yet many people swear by it.
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Post by sliderocker on Mar 17, 2017 22:44:58 GMT -5
well, I have heard more positive things about Kratom than negative. Everyone reacts differently. When I first tried Kratom I mixed it with orange juice (I don't like tea), and it was just gross and made me throw up. .Big Mistake LOL Then I used capsules which worked better for me. I have chronic muscle spasms and pain, and now lower back pain. Not a fan of painkillers so I researched Kratom and by asking others.. I prefer natural vs rx's . I did try Marijuana but it has horrible effects on me and makes me sick... yet many people swear by it. I'd like to try the capsules to see if they could help lessen my diabetic neuropathy pain, which has gotten worse and continues to worsen. I am curious about it and after seeing PoP80's concern about it being addictive and other problems, typed it into the search bars on medical websites.It is considered an opioid, which probably means it classed as a Class II drug. It is considered addictive and can cause death but a this stage, I'm willing to try almost anything to shut down the pain. Every drug I've been prescribed for the problem didn't work and that includes Lyrica. Is the natural version available in the health food stores? Or maybe Wal-Marts or Targets or CVS or Walgreens? I'm getting desperate. With Linda's Parkinson's and diabetes, I'm almost betting she has a problem with diabetic neuropathy as well since the diabetic neuropathy affects the feet first and if the diabetic is lucky, it stays there and doesn't move up the body.
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Post by the Scribe on Mar 17, 2017 23:12:45 GMT -5
I have the extremely painful neuropathy and muscle spasms without diabetes. My neurologist says mine is caused by high vitamin B 6. So I stopped all vitamins for about a year now and the neuropathy is worse and I get charley horses (spasms) everywhere. These expensive doctors have no idea what they are talking about. Lyrica almost caused me to have a stroke after one pill. So what does this doctor do? He prescribes a pain killer in the same lyrica family and says if it causes another stroke type issue let me know. I am going to have my primary care physician check my vitamin levels again just for the record. Then I am going back on my youngevity protocol (Dr. Wallach), On my own I discovered that certain genes you inherit can cause certain vitamins to NOT be assimilated so it makes it look like you have too much when in fact you aren't getting enough. I tested positive for that mthfr gene problem just as I suspected. That gene effects B vitamins but when I told my neurologist he got a bit indignant that I would question him and even be more familiar than him on this stuff. You have to take charge of your own health as not all people are the same and same illnesses can be caused by different things. Thank god for the internet and forums that are open to just about every topic you can imagine. We are not alone. There is bound to be others in the same boat and they may have gotten both paddles back and are willing to share. So hang in there.
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Post by Dianna on Mar 17, 2017 23:27:12 GMT -5
I am sorry to hear about your pain. I remember you said you suffered from neuropathy. What I can tell you is Kratom is not an opioid. It targets the same brain receptors as an opioid.. I can send you better material tomorrow.. Last July the DEA said they would Ban Kratom the following Sept to a schedule 1. with lots of protesting and testimonials they put the ban on hold. So it is legal to buy Kratom online or from a vendor in your area.. I would also check with your dr before trying this. I know others with medical issues check with their physicians first .. and as far as I know, there have been no problems. Kratom is banned is several states… I think OK is good.. This is the only thing, natural I have found to help me. When I have pain I take Kratom White Borneo or Maeng Da.. Hope this helps you Slide.
Update.. Actually Kratom is only banned in a few states.. Alabama.. Florida, Arkansas, TN, Wisconsin and Indiana. maybe 1 other not sure. I'll check tomorrow and send
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Post by philly on Mar 18, 2017 13:37:01 GMT -5
I'm sure Linda's tried marijuana. But this video is interesting nonetheless.
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Post by the Scribe on Mar 18, 2017 16:59:22 GMT -5
I made it through my whole life without ever even trying to smoke pot as I don't care for smoke of any kind. Makes me sick just being around smoke. But if it works so well for pain and the symptoms of Parkinson's and other diseases I have to wonder HOW MANY pot heads out there that smoke it regularly have these diseases and pain and they don't even know it? I suppose they wouldn't know about their maladies until they stopped smoking it. At the very least is should be allowed for medical use. Stem cell therapy and research is another potential cure for just about everything is also something that should never have been stymied.
Anyone ever heard of BEMER? FDA approved but I wonder if insurance would cover the cost? It is about 6 months of my cat food budget but they even have a pet Bemer. No, this isn't a BMW. This seems better than meds or in the very least safer. It is an energy healing device.
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Post by sliderocker on Mar 18, 2017 19:52:28 GMT -5
I am sorry to hear about your pain. I remember you said you suffered from neuropathy. What I can tell you is Kratom is not an opioid. It targets the same brain receptors as an opioid.. I can send you better material tomorrow.. Last July the DEA said they would Ban Kratom the following Sept to a schedule 1. with lots of protesting and testimonials they put the ban on hold. So it is legal to buy Kratom online or from a vendor in your area.. I would also check with your dr before trying this. I know others with medical issues check with their physicians first .. and as far as I know, there have been no problems. Kratom is banned is several states… I think OK is good.. This is the only thing, natural I have found to help me. When I have pain I take Kratom White Borneo or Maeng Da.. Hope this helps you Slide. Update.. Actually Kratom is only banned in a few states.. Alabama.. Florida, Arkansas, TN, Wisconsin and Indiana. maybe 1 other not sure. I'll check tomorrow and send I'll be buying Kratom shortly to give it a try. I'll probably wait until I get paid again so I can build up the money in my bank account as I want to buy the colors of Kratom needed to work on the pain. Will let you know how everything works out.
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Post by the Scribe on Apr 1, 2017 1:49:12 GMT -5
Linda Ronstadt praises Emmylou Harris for Parkinson's support
Singer LINDA RONSTADT has thanked fellow veteran star EMMYLOU HARRIS for keeping her spirits up during dark days as she battles Parkinson's disease.
PUBLISHED: 18:38, Mon, May 5, 2014
The multi-Grammy Award winner revealed last year (13) that she has been diagnosed with the condition, which has robbed her of her singing voice.
Now she has told how she spends most of her time lying on a recliner at her home in San Francisco, California, without even a record player for company, but has praised Harris for her constant support, and also thanked other friends who travel to her home to play mini-concerts for her.
Ronstadt tells Mojo magazine, "I spend most of my days like this. I don't like being upright really. I look out the window and I read stuff, or friends come to visit. It is how it is... (Harris) has been a very devoted friend. She calls me a lot. We talk about the stuff she's doing, who she's singing with, where she's finding new songs. I love it; it's all I've got now.
"I can't sing any more but I can hear like a professional singer, I've got a big brain map in my head for singing, so I enjoy listening. But live music, mainly - people come to my house and play something. I don't have a record player - isn't that terrible?"
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Post by the Scribe on Apr 11, 2017 5:03:03 GMT -5
Book | The Enlightened Mr. Parkinson: The Pioneering Life of a Forgotten Surgeon April 8, 2017
The Enlightened Mr Parkinson
Something different today – but certainly keeping in line with our interest in all things Parkinson-related. As many readers will be aware, 2017 is the 200th anniversary of the first description of Parkinson’s disease by one James Parkinson (1817).
Just in time for Parkinson’s Awareness week (next week), a new book has been published that outlines the life of the great man behind the disease. This book, however, takes a very different look at James. While discussing his medical contributions, it also provides a deeper understanding of all of the ‘other stuff’ he did.
In today’s post, we have our first ever author interview.
This week ‘The Enlightened Mr. Parkinson: The Pioneering Life of a Forgotten English Surgeon’ by Cherry Lewis was published by Icon Books Ltd.
In the book, Dr Lewis provides a new angle on the life of James Parkinson: while discussing many of the medical related activities of his life as several other books have done, Lewis also provides insight into Parkinson’s interest in the geological sciences.
The-Enlightened-Mr-Parkinson-cover
We have previously communicated with Dr Cherry Lewis about our interest in James Parkinson, and when we heard that her book was being published this week we reached out and asked if she would mind answering a few questions about the book.
Good soul that she is, she readily agreed.
That said, let’s begin:
Hi Cherry, thank you for agreeing to do this. Please introduce yourself to the readers.
I am an Honorary Research Fellow in the Department of Earth Sciences at the University of Bristol. A geologist by training, I have worked in the oil industry as well as in the press office at the University of Bristol where I ‘translated’ developments in science and medicine for the general public. I now write on the history of geology and other sciences.
And why have you written a book about James Parkinson? What was your interest in him?
Parkinson wrote the first scientific account of fossils – a three-volume work entitled, ‘Organic Remains of a Former World’.
1-challinor-collection-1804
Organic Remains of a Former World by James Parkinson, London, 1804. Source: Aberrarebooks
I felt Parkinson’s understanding of geology and fossils had never been properly examined and interpreted before. I wanted to put the record straight.
Were you familiar with his life story before you started?
Once I started, I realised that there were other biographies, but these tended to focus on his medical work and didn’t cover his most important work – his study of fossils – in any depth.
What surprised you in your research on JP?
That he had worked with Edward Jenner shortly after Jenner discovered the cow pox vaccine. Parkinson gave Jenner his dissecting microscope. What was the most interesting episode in JP’s life for you personally?
The intellectual struggle he underwent between the conventional religious convictions he had been brought up with and the truth about the age and creation of the Earth that was revealed to him through fossils. Like Darwin 50 years later, the version he presented to his audience through his books was not always what he believed himself.
What aspect of JP’s life do you wish people knew more about?
Most people have no idea who James Parkinson was at all so I’ll just be happy if they have now at least heard of him. But I would really like them to know that not only did he identify Parkinson’s disease but that during his lifetime he was internationally famous for his geological work and many fossils were named in his honour. So when the Royal College of Surgeons awarded him their first Gold Medal it was not for his medical work, nor even his Essay on the Shaking Palsy, but for his ‘splendid work on Organic remains’. It is my contention that while he would have been proud to know a disease had been named in his memory, I suspect he would rather be remembered for his work on fossils.
And finally where can readers find your book?
The book is available on Amazon.
You can hear me talking about the book on BBC London’s Robert Elms show, at 1 hour 37 minutes into the programme: www.bbc.co.uk/programmes/p04xf5nl
Fantastic. Thank you very much for your time. I’m sure the readers will be interested in buying the book and reading more.
One last note.
We here at the SoPD would also like to thank Dr Lewis for correcting us on the fact that James Parkinson was never actually a ‘Dr’.
He was simply Mr James Parkinson.
James (like his father) was trained as an apothecary (a medical practitioner who formulated and dispensed medications) and surgeon.
In the 18/19th centuries, physicians had to undergo formal university training to gain possession of a degree in medicine before they could begin to practice medicine. With this degree – a doctorate – the individual was entitled to call themselves a ‘Doctor of Medicine’ or simply Doctor (Source: Rcseng). James never went to university, and thus he is not a ‘Dr’.
An interesting fact – a fascinating read. We recommend it.
a different take:Published on Feb 26, 2017
Solutions for Parkinson's Disease . Dr. John Bergman
Parkinson's Disease affects over 10 million people worldwide, but nobody seems to understand what causes it. In this video, Dr. Bergman explains exactly what causes Parkinson's and effective natural solutions to restore normal function.
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Post by the Scribe on Apr 28, 2017 13:45:56 GMT -5
The cause for Parkinson's may be as simple as improper balance of "gut bacteria." And the cure may be the rebalancing of it. It also appears that Chronic Fatigue Syndrome may have a similar cause. Could Alzheimer's have the same cause because they are very similar types of diseases?
Wouldn't it be wonderful if Linda's FIX may be as simple as re-balancing her gut bacteria with pre and probiotics and a fecal transplant?
If I had any one of these types of diseases I would find out all I could about it and start taking these supplements. This is fairly new information however earlier in this thread I mentioned the work of Dr. Joel Wallach who is one of the Fathers of Epigenetics which is where this theory lies. He has been talking about this as the cause of Parkinson's and other diseases and is being proven right. Time for those calling him a quack to eat their words.
The medical and drug industries will be fighting this as they stand to lose billions to the supplement industry. We need a reboot of our entire healthcare industry to include a holistic, integrated approach.
Keep in mind NOT all supplements are created equal. Do your research on those that are the most viable.
Gut Bacteria Imbalance Found To Be A Cause Of Parkinson’s Disease It is only in recent years that science has begun to explore the role that bacteria in the digestive system play in the context of human health.
A recent study has discovered that they are much more influential than previously thought, directly affecting the brain.
The Brain-Gut Connection
The human body contains ten times more bacteria than it does human cells. It is estimated that the gut (where most of these bacteria live) contains over three million unique bacterial genes of one thousand different species—one hundred fifty times more than our own genes (1). Most of these bacteria are not only beneficial but necessary for proper body function. Unfriendly bacteria can cause illness but the body knows enough to attack and kill those that are harmful. If, however, the “good” bacteria are compromised, the immune system weakens and disease can ensue. Studies into all the ways in which internal bacteria affect health have revealed some surprising results.
A common perception is that the brain controls all the body’s systems. Links have been found that show the brain’s influence on the gut function. But, it turns out, that it’s a two-way street: microbiota in the gastrointestinal tract influence brain function, including cognition, memory, and motor activity.
An Unlikely Parkinson’s Disease Cause
Parkinson’s disease is a chronic and progressive disorder that affects motor control and cognition. Neurons in the brain that regulate the production of the hormone dopamine begin to die. the reduction in dopamine levels affects motor function, resulting in:
• Tremors in the head, hands, arms, and legs • Stiff or rigid arms, legs, and torso • Slow body movement • Loss of balance, sometimes progressing to the inability to stand • Sleep irregularity • Loss of the sense of smell • Change in voice
The exact cause of Parkinson’s disease has been previously unknown. It has been theorized that it is partly genetic but predisposition doesn’t always manifest in symptoms. Environmental factors such as herbicides and pesticides, pharmaceuticals, chronic inflammation (the result of any combination of factors, including poor dietary habits, aspartame, food additives, stress, and lack of exercise), and other toxins contribute to the risk of developing Parkinson’s and other neurological diseases.
Current Research
In a recent study, the two-way street between the brain and the gut were very clearly observed.
The results of the study begin with: “The intestinal microbiota influence neurodevelopment, modulate behavior, and contribute to neurological disorders. However, a functional link between gut bacteria and neurodegenerative diseases remains unexplored.”
Synucleinopathies are the group of neurodegenerative disorders characterized by the collection of α-synuclein proteins around neurons (nerve cells) and glia (brain cells that support neurons, transporting nutrition and removing waste). α-synuclein is a protein normally found in the brain; in the case of synucleinopathies, there occurs an over-accumulation of them. Parkinson’s disease is included in this group. The mice used in the study were treated to over-produce α-synuclein. Scientists found that the administration of antibiotics exacerbated the loss of motor control and other Parkinson’s symptoms. When the mice were orally fed probiotics (normal gastrointestinal bacteria), motor function improved and brain activity increased. Other groups of α-synuclein over-producing mice in the study were given microbiota directly from healthy people and people diagnosed with Parkinson’s. The reaction in the mice: symptoms worsened after receiving bacteria from the Parkinson’s donor group.
The study concluded: “These findings reveal that gut bacteria regulate movement disorders in mice and suggest that alterations in the human microbiome represent a risk factor for PD [Parkinson’s Disease].” (2) The Importance Of Gut Bacteria
Synucleinopathies are not the only neurological conditions affected by gut bacteria.
If further proof is needed of the connection between healthy bacterial levels and the brain, here it is. A 2013 study linked gut bacteria to autism spectrum disorders (ASD). Symptoms were stimulated by the introduction of harmful bacteria and alleviated with the administration of probiotic bacteria. References to other studies point to a similar connection between brain and gut when studying multiple sclerosis, anxiety, and emotional instability.
“…microbial shifts within the gut of a mouse resulted in changes of metabolites in the serum and that these lead to the onset of autism-like behaviors. Moreover, administering a beneficial bacterium, Bacteroides fragilis, reversed the physiological, neurological, and immunological anomalies.” (3)
This would explain why, in some cases, ASD symptoms disappear when a child’s diet is changed.
We are not meant to eat all the junk in processed and genetically modified foods, as they throw everything out of whack in our digestive systems and—as we now know—in our brains as well.
more resources:
www.parkinson.org/find-help/blogs/whats-hot/january-2015
www.parkinsons.org.uk/news/23-may-2011/gut-bacteria-linked-parkinsons
www.bbc.com/news/health-38173287
www.bbc.com/news/health-38173287
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Post by the Scribe on Jun 22, 2017 5:25:12 GMT -5
This was a topic on the radio tonight, again. It is becoming clear that Parkinson's and OTHER similar neurological maladies like Alzheimer's start in the GUT. If I had either of these diseases or had it in my family I would sure as hell make sure I was on the best and highest quality probiotics and supplements including pre-biotics. Dr. Joel Wallach whom I started this thread out with information about and whom many regard as a quack is proven to be right. That is why he is considered the father of and one of the founders of the new science of Epigenetics. Our DNA can be changed through diet and as a result so can our diseases be cured. For instance Wallach has steadfastly maintained that Alzheimer's is a result of a lack of cholesterol in the body exacerbated by the anti cholesterol craze and statin drugs to lower cholesterol in the past few decades. How to combat? Eat a DOZEN EGGS easy over so the yolk is runny. Cook with butter. Avoid ALL the vegetable oils including Olive, Coconut, etc. There is plenty of stuff from Dr. Joel Wallach on the internet. Anyway, this is important. I hope Linda is paying attention. Dr. Wallach also spoke tonight of a man from Canada named David Deitrich (a billionaire) who had Parkinson's so badly he couldn't walk and was becoming a vegetable. Wallach got him on his program and a few months later at one of his lectures David showed up looking like he never had the disease. Among the things on his program was (because of his 260 lb size) he needed to eat 2 dozen eggs a day. It is a shame that most doctors today, especially in the US have no clue about any of this stuff and are so bound up in their own political dogma. People who are sick have no time to waste and doing these things (while not particularly cheap) is a must. What's that saying "You can lead a horse to water but you cannot make it drink!" Same applies here. Believe what you will.Parkinson's disease 'may start in gut'
By James Gallagher Health and science reporter, BBC News website • 2 December 2016
• From the section Health Image copyright Thinkstock Image caption One of the main symptoms of Parkinson's is an uncontrolled tremor Scientists in California say they have transformed understanding of Parkinson's disease.
Their animal experiments, published in the journal Cell, suggest the brain disorder may be caused by bacteria living in the gut.
The findings could eventually lead to new ways of treating the disease, such as drugs to kill gut bugs or probiotics.
Experts said the results opened an "exciting new avenue of study".
In Parkinson's disease the brain is progressively damaged, leading to patients experiencing a tremor and difficulty moving.
Researchers used mice genetically programmed to develop Parkinson's as they produced very high levels of the protein alpha-synuclein, which is associated with damage in the brains of Parkinson's patients.
But only those animals with bacteria in their stomachs developed symptoms. Sterile mice remained healthy.
Further tests showed transplanting bacteria from Parkinson's patients to mice led to more symptoms than bacteria taken from healthy people.
Dr Timothy Sampson, one of the researchers at the California Institute of Technology, said: "This was the 'eureka' moment, the mice were genetically identical, the only difference was the presence or absence of gut microbiota.
"Now we were quite confident that gut bacteria regulate, and are even required for, the symptoms of Parkinson's disease."
'Paradigm shift'
The scientists believe the bacteria are releasing chemicals that over-activate parts of the brain, leading to damage.
The bacteria can break down fibre into short-chain fatty acids. It is thought an imbalance in these chemicals triggers the immune cells in the brain to cause damage.
Image copyright Caltech Image caption Immune cells in the brain - microglia - may be activated by bacteria in the gut
Dr Sarkis Mazmanian said: "We have discovered for the first time a biological link between the gut microbiome and Parkinson's disease.
"More generally, this research reveals that a neurodegenerative disease may have its origins in the gut and not only in the brain as had been previously thought.
"The discovery that changes in the microbiome may be involved in Parkinson's disease is a paradigm shift and opens entirely new possibilities for treating patients."
Parkinson's is currently incurable. (NOT ACCORDING TO DR. WALLACH. AND HE HAS PROVED IT.)
While the findings need to be confirmed in people, but the researchers hope that drugs that work in the digestive system or even probiotics may become new therapies for the disease.
The trillions of bacteria that live in the gut are hugely important to health, so wiping them out completely is not an option.
Dr Arthur Roach, from the charity Parkinson's UK, said: "In recent years, evidence has been growing that Parkinson's may begin in the gut, but the chain of events involved has so far remained a mystery.
"This work opens an exciting new avenue of study on the gut-brain connection in Parkinson's.
"There are still many questions to answer, but we hope this will trigger more research that will ultimately revolutionise treatment options for Parkinson's."
Dr Patrick Lewis, from the University of Reading, said: "This study really does reinforce the idea that examining what goes on in the stomach of people with Parkinson's could provide really important insights into what happens in disease, and potentially a new area of biology to target in trying to slow down or halt the changes in the brain."
Follow James on Twitter.
www.bbc.com/news/health-38173287 Could Parkinson's disease start in the gut? April 26, 2017 Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's disease. Credit: Wikipedia Parkinson's disease may start in the gut and spread to the brain via the vagus nerve, according to a study published in the April 26, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology. The vagus nerve extends from the brainstem to the abdomen and controls unconscious body processes like heart rate and food digestion.
The preliminary study examined people who had resection surgery, removing the main trunk or branches of the vagus nerve. The surgery, called vagotomy, is used for people with ulcers. Researchers used national registers in Sweden to compare 9,430 people who had a vagotomy over a 40-year period to 377,200 people from the general population. During that time, 101 people who had a vagotomy developed Parkinson's disease, or 1.07 percent, compared to 4,829 people in the control group, or 1.28 percent. This difference was not significant.
But when researchers analyzed the results for the two different types of vagotomy surgery, they found that people who had a truncal vagotomy at least five years earlier were less likely to develop Parkinson's disease than those who had not had the surgery and had been followed for at least five years. In a truncal vagotomy, the nerve trunk is fully resected. In a selective vagotomy, only some branches of the nerve are resected.
A total of 19 people who had truncal vagotomy at least five years earlier developed the disease, or 0.78 percent, compared to 3,932 people who had no surgery and had been followed for at least five years, at 1.15 percent. By contrast, 60 people who had selective vagotomy five years earlier developed Parkinson's disease, or 1.08 percent.
After adjusting for factors such as chronic obstructive pulmonary disease, diabetes, arthritis and other conditions, researchers found that people who had a truncal vagotomy at least five years before were 40 percent less likely to develop Parkinson's disease than those who had not had the surgery and had been followed for at least five years.
"These results provide preliminary evidence that Parkinson's disease may start in the gut," said study author Bojing Liu, MSc, of the Karolinska Instituet in Stockholm, Sweden. "Other evidence for this hypothesis is that people with Parkinson's disease often have gastrointestinal problems such as constipation, that can start decades before they develop the disease. In addition, other studies have shown that people who will later develop Parkinson's disease have a protein believed to play a key role in Parkinson's disease in their gut."
The theory is that these proteins can fold in the wrong way and spread that mistake from cell to cell.
"Much more research is needed to test this theory and to help us understand the role this may play in the development of Parkinson's," Liu said. Additionally, since Parkinson's is a syndrome, there may be multiple causes and pathways.
Even though the study was large, Liu said one limitation was small numbers in certain subgroups. Also, the researchers could not control for all potential factors that could affect the risk of Parkinson's disease, such as smoking, coffee drinking or genetics.
medicalxpress.com/news/2017-04-parkinson-disease-gut.html
Read more at: medicalxpress.com/news/2017-04-parkinson-disease-gut.html#jCp
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Post by Diana Shepard on Jun 26, 2017 16:17:34 GMT -5
Many are misdiagnosed with Parkinson's Disease when they actually have Lyme Disease. Lyme Disease is caused by a spirochete shaped bacteria (Borellia Burgdorferi), similar to Syphilis which is also a spirochete. It can attack any where in the body. It can mimic almost any health issue (Parkinson's, Alzheimer's, ALS, Lupus, Chronic Fatigue, Arthritis, Heart Palpatations, Heart Blockages, MS, IBS...just to name a few...the list is endless. Lyme can attack anywhere in the body. Many people are dying of some of these diseases when they actually have Lyme. Lyme tests are not accurate which is why many are falling through the cracks. If you look up youtube Lyme, and Alan MacDonald, MD, Dr. Al Miller, or Dr. Horowitz. Look up ILADS. Look up "Lyme and Parkinson's"...there's a wealth of information out there. Why am I so passionate...I have Lyme!
Everyone needs to learn about Lyme...it could save a life...it saved mine!!! I had to find a Lyme Literate Medical Doctor to get help. Most doctors know very little about Lyme. Mayo Clinic knows very little about Lyme. If you have a negative test result with some positive bands, they will not treat unless you have five positive bands. Some bands should stand on there own as a positive result as they are specific to Lyme. There is a big divide in the medical community about Lyme. "Under Our Skin" and "Emergence" (sequel) are documentaries about Lyme Disease. Definitely worth watching if you have a loved one with health issues that the medical community is having a difficult time understanding, consider Lyme. You must find a Lyme Literate Medical Doctor if you want to get treated. Not everyone gets the bullseye rash from the tick. Also, many who get Lyme also get co-infections (Babesia, Erhlichia, Mycoplasma, Bartonella, Rocky Mountain Spotted Fever, etc.) at the same time making treatment more complex.
I pray Linda Ronstadt gets checked by a Lyme Literate Medical Doctor and gets a IgeneX Lyme Test (more sensitive than other Western Blot Tests and includes all the bands). I hate to think that she fell through the cracks and was misdiagnosed.
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Post by PoP80 on Jun 26, 2017 16:48:36 GMT -5
From what I recall, Linda mentioned that she did have a tick bite from one of her cows many years ago. It's possible that it was one of the triggers that may have contributed to her Parkinson's, but she did have all the tests that confirmed the diagnosis of PD. I know that Lyme disease is often misdiagnosed and can lead to a host of serious health problems. I'm glad you finally found the right doctor who correctly diagnosed and treated your Lyme disease.
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Post by the Scribe on Jun 26, 2017 17:11:35 GMT -5
My understanding of Lyme is that if treated with antibiotics right away it will take care of the problem. Not sure if that protocol is not followed or if it is not enough. Linda said she thought she got a tick bite from a tick on Luna the cow. I didn't think there were many ticks in the desert unless she was living somewhere else at the time it happened. It wasn't clear to me. Why not treat both problems at the same time? I always like to cover my bases as long as one doesn't interfere with the other.
So what is the treatment? Not just antibiotics?
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Post by PoP80 on Jun 26, 2017 17:45:48 GMT -5
From what I know, oral antibiotics are only effective if Lyme is detected early. It can cause neurological and cardiac problems that may be treated with IV antibiotics like penicillin. Once the disease has done significant damage over time, it is difficult to treat and becomes a chronic disease.
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Post by the Scribe on Jun 26, 2017 17:51:05 GMT -5
That would be the time to begin Dr. Wallach's epigenetic protocol. It will effectively alter dna for a cure.
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Post by Dianna on Jun 26, 2017 19:44:35 GMT -5
Didn't one of Linda's grandmothers have Parkinsons ..and could have played a role in it. ?
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Post by the Scribe on Jun 26, 2017 21:12:19 GMT -5
Didn't one of Linda's grandmothers have Parkinsons ..and could have played a role in it. ?
Genetics, dna, lyme disease, being a boxer and problems originating in the gut are some of the ways thought to bring on symptoms. Research is beginning to find it is reversible but it could be decades before doctors are on board with it. Too late for most. It could be possible that grandma's gut bacteria got shared with family members or passed down through the birthing process. It happens with animals why not people? One needs to keep an open mind and think outside the box if we want to get to the bottom of these diseases.
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Post by musedeva on Jul 4, 2017 1:04:11 GMT -5
My GaWD!!! LINDA if you READ here!!! DO THE ABOVE!!! Dr. Wallach is very Respected!!! START ON BIO K!!! BEST PROBIOTIC OUT THERE!!! Get a case of it, it is at health food stores and refrigerated!!! Used this for years, off and on myself, its very expensive BUT WORTH IT!! www.biokplus.com/en_us/about-probiotics#why-bio-k"INTERESTING FACT : 70% of the immune system’s cells are found in the intestinal tract, so it goes without saying that your immune system can be thrown out of whack when your intestinal flora is unbalanced, like during a round of antibiotics 10!"
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Post by musedeva on Jul 4, 2017 1:05:32 GMT -5
....seems that Linda doesnt go too much outside mainstream this that or the other.....hope she trys to reach
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Post by sliderocker on Jul 4, 2017 19:07:36 GMT -5
My GaWD!!! LINDA if you READ here!!! DO THE ABOVE!!! Dr. Wallach is very Respected!!! START ON BIO K!!! BEST PROBIOTIC OUT THERE!!! Get a case of it, it is at health food stores and refrigerated!!! Used this for years, off and on myself, its very expensive BUT WORTH IT!! www.biokplus.com/en_us/about-probiotics#why-bio-k"INTERESTING FACT : 70% of the immune system’s cells are found in the intestinal tract, so it goes without saying that your immune system can be thrown out of whack when your intestinal flora is unbalanced, like during a round of antibiotics 10!" I'd recommend that Linda look into Bio-K, but do a little bit of research before she purchased the pro-biotic. She doesn't want to do anything that is going to cause more problems on the other health issues she has. She mentioned in the past she's diabetic. Would the probiotic negatively affect her diabetes or any medications she may take to combat the illness? Likewise, her thyroid problem, could the probiotic negatively affect any medication she may have to take for that? My concern is that however she treats her illness, I want her to err on the safe side when it comes to her health. Many alt-medicines may in fact be an in behind the counter medication she may already be taking. If she was taking an alt-medicine and it contained an ingredient already used in a medication she's taking, taking too much of it could make it toxic or even lethal for her.
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Post by the Scribe on Aug 2, 2017 0:23:13 GMT -5
I stumbled onto this article about scientific studies regarding GUT BACTERIA. More and more studies are showing its effect on the human body and disease INCLUDING diseases like Parkinson's and Alzheimer's. This is fascinating and the thing to take away is that everyone, especially those who are either suffering from these diseases or have a history of it in their family (as gut bacteria is passed on in the birth canal so what we thought of as genetic ISN'T always genetic) should take heed. Research pre and probiotics for the highest qualities based on studies and START TAKING these supplements.
Gut Feelings www.buffalo.edu/atbuffalo/article-page-spring-2016.host.html/content/shared/www/atbuffalo/articles/Spring-2016/features/gut-feelings.detail.html
The microbiome, poised to transform modern medicine—perhaps even to alter our perception of what it is to be human—is still largely a mystery. But researchers at UB and elsewhere are on the path to solving it.
“Our work at UB has grown exponentially, and it’s terrifically exciting. What’s happening here and elsewhere has the potential to rewrite the microbiology textbooks we all learned from.” Robert Genco
Much like the Earth itself, our bodies teem with life that is not, strictly speaking, our own. Trillions of tiny organisms, including bacteria, fungi, viruses and other one-celled microbes invisible to the naked eye, reside in and on us in specialized communities. Together they form what’s called the microbiome—our body’s complete ecosystem of microorganisms.
To illustrate just how prolific these little guys are, our microbes are estimated to outnumber the body’s cells 10 to 1; together they weigh between one and three pounds in an average-size adult. And they’re not just along for the ride. Many organisms making up the microbiome play well with their hosts and with each other, helping control and maintain our immune system, weight, hormone levels and other vital life functions. But balance is the key. All microbes are opportunistic and can flood our systems when competing microbes are absent; some, like the E. coli bacterium, can do quite a bit of harm as a result, causing serious illness or, if they succeed in overwhelming the microbial and bodily defenses, even killing their host.
Consequently, it’s the nastier microbes that often dominate headlines, as the medical community rushes to develop and prescribe ever more potent antibiotics to combat new strains. However, scientists, physicians and the public are starting to pay more attention to our body’s beneficial microbes, realizing the powerful, healing roles they play in human health and well-being.
Microbiologist David Relman, who co-directs the Center for International Security and Cooperation at Stanford University, is among those who are attempting to shift the focus of infectious disease research to include not just the pathogenic microbes but the “good guys” as well. Speaking about the microbiome at UB this past fall as part of President Tripathi’s Critical Conversations series, Relman, one of the country’s top researchers pursuing this relatively new field, seemed at times to be in awe of our dual biologies—that of our own cells and that of the cells of our microbial partners. “We are one type of life among many, many others. Nothing exists in isolation,” he said.
Indeed, human microbes have been around as long as we have, and thrive in different amounts and groups inside our body’s many habitats, including in our intestines and mouth, on our skin, and in our nostrils. These groups can be quite different from each other, but, as Relman described, there are also similarities among microbial communities around the world. For instance, a North American’s gut bacteria, or flora, may have more in common with the gut bacteria of someone in Japan than they do with the bacteria in that individual’s own gums.
Microbes, like our own genes, may also predict our future health. Bacteria found in a pregnant woman’s vagina are passed along to the baby’s underdeveloped gastrointestinal tract at birth and, along with breast milk, help seed the newborn’s gut flora with the right microbial mix to help it—and the child—develop normally. Some researchers suspect that birth by cesarean section and formula feeding may be linked to health issues later in life because the infant wasn’t exposed to that very specific combination of beneficial bacteria.
KEEP READING www.buffalo.edu/atbuffalo/article-page-spring-2016.host.html/content/shared/www/atbuffalo/articles/Spring-2016/features/gut-feelings.detail.html
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Post by the Scribe on Aug 5, 2017 0:17:44 GMT -5
Diabetes Drug Slows Experimental Parkinson’s Disease Progression.
GRAND RAPIDS, Mich. (Dec. 7, 2016)—A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world’s first treatment to impede the progression of Parkinson’s disease (PD) following publication of research findings today in the journal Science Translational Medicine. “We hope this will be a watershed moment for millions of people living with Parkinson’s disease. All of our research in Parkinson’s models suggests this drug could potentially slow the disease’s progression in people as well.” - Patrik Brundin, M.D., Ph.D., director Van Andel Research Institute’s Center for Neurodegenerative Science, chairman Linked Clinical Trials Committee, and the study’s senior author.
"Until now, Parkinson’s treatments have focused on symptom management. If successful in human trials, MSDC-0160 would be the world’s first therapy to treat the underlying disease and slow its progression—potentially improving quality of life and preventing the occurrence of falls and cognitive decline. It may also reduce or delay the need for medications that can have debilitating side effects," says Professor Brundin.
Tom Isaacs, co-founder of The Cure Parkinson’s Trust who has lived with Parkinson’s for 22 years, says MSDC-0160 represents one of the most promising treatments the Trust’s international consortium has seen to date.
“Our scientific team has evaluated more than 120 potential treatments for Parkinson’s disease, and MSDC-0160 offers the genuine prospect of being a breakthrough that could make a significant and permanent impact on people’s lives in the near future,” says Tom. “We are working tirelessly to move this drug into human trials as quickly as possible in our pursuit of a cure.”
MSDC-0160 was developed by Michigan-based company, Metabolic Solutions Development Company (MSDC), in Kalamazoo, US to treat type 2 diabetes. In 2012, Professor Patrik Brundin recognised it as an exciting drug candidate because of its mode of action, proven safety in people, local availability and the start-up company’s interest in collaborating on drug repurposing initiatives. After four years of work, the effects of the drug in the laboratory exceeded Professor Brundin’s expectations.
The novelty of MSDC-0160 stems from a recently revived revelation that Parkinson’s may originate, at least partially, in the body’s energy metabolism. The new drug appears to regulate mitochondrial function in brain cells and restore the cells’ ability to convert basic nutrients into energy. Consequently, the cells’ ability to handle potentially harmful proteins (alpha-synuclein) is normalised, which leads to reduced inflammation and less nerve cell death. “Parkinson’s disease and diabetes may have vastly different symptoms with unrelated patient outcomes; however, we’re discovering they share many underlying mechanisms at the molecular level and respond similarly to a new class of insulin sensitizers like MSDC-0160.” - Jerry Colca, Ph.D., co-founder, president and chief scientific officer of MSDC.
The Cure Parkinson’s Trust and Van Andel Research Institute are currently working with MSDC to address regulatory issues and obtain funding to organise the clinical trial, which Professor Brundin hopes can begin sometime in 2017.
Funding for the research was provided by Van Andel Research Institute, The Cure Parkinson’s Trust, the Campbell Foundation, and the Spica Foundation.
The paper’s authors include Anamitra Ghosh, Trevor Tyson, Sonia George, Erin N. Hildebrandt, Jennifer A. Steiner, Zachary Madaj, Emily Schulz, Emily Machiela, Martha L. Escobar Galvis, Jeremy M. Van Raamsdonk and Patrik Brundin, all of Van Andel Research Institute; William G. McDonald and Jerry R. Colca, both of Metabolic Solutions Development Company; and Jeffrey H. Kordower, of Rush University Medical Center and Van Andel Research Institute.
Research Article Source: Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson’s disease - Science Translational Medicine 7th December 2016
Published: 5th December, 2016
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Post by musedeva on Aug 5, 2017 2:09:21 GMT -5
I SWEAR by BIO K and my Hindu Priests!!!heheheh
BTW...they have BK in Strawberry now! Delic
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Post by ausfan2 on Aug 5, 2017 7:20:37 GMT -5
Diabetes drug offers hope for Parkinson’s AAP, The Daily Telegraph NSW Australia August 5, 2017
An international “landmark” study has shown it may be possible to safely slow the progression of Parkinson’s disease using an existing diabetes drug, providing hope for those with the debilitating disease.
The safety trial, published in The Lancet and funded by The Michael J Fox Foundation for Parkinson’s Research (MJFF), found that people with Parkinson’s who received weekly injections of exenatide for one year performed better in movement (motor) tests than those who were on a placebo.
“This is a very promising finding, as the drug holds potential to affect the course of the disease itself, and not merely the symptoms,” said the study’s senior author, Professor Tom Foltynie at the UCL Institute of Neurology. Currently, existing treatments relieve most of the symptoms for some years, but the disease continues to worsen.
The researchers followed 60 people with moderate Parkinson’s disease at the UK’s National Hospital for Neurology and Neurosurgery (NHNN).
Participants were randomly assigned to receive injections of exenatide or placebo once a week for 48 weeks in addition to their regular medication, followed by a 12-week ‘washout’ period. Patients given exantide showed improvements in their movement, which persisted after the 12-week follow-up.
Those who had injected the placebo showed a decline in their motor scores at both the 48 and 60 week tests.
Whether exenatide affects the underlying disease or just its symptoms is uncertain, the researchers say. Further, longer-term trials are required. Australian Professor Bryce Vissel, Director of the Centre for Neuroscience and Regenerative Medicine at the University of Technology Sydney, has hailed the study as “exceptionally important”.
He says the finding provides hope of a new way forward.
“Despite decades of research efforts, there are no cures and the disease continues to worsen over time until the symptomatic treatments are less and less useful. No currently available treatments slow the underlying disease process in humans. There is an urgent need for treatments that slow the underlying disease,” said Prof Vissel.
“If this finding holds up to further investigations, this will have been a watershed for a disease that affects approximately 70,000 Australians from all walks of life,” he said.
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Post by the Scribe on Aug 25, 2017 5:02:43 GMT -5
NPR highlighted yet ANOTHER story on the growing importance (newly discovered) of GUT BACTERIA to cut disease, especially auto immune diseases. It has already been associated to Parkinson's, Alzheimer's and Autism.Is The Secret To A Healthier Microbiome Hidden In The Hadza Diet?Listen· 2:26 2:26 ondemand.npr.org/anon.npr-mp3/npr/atc/2017/08/20170824_atc_extinct_microbiome.mp3?orgId=1&topicId=1031&d=146&p=2&story=545631521&t=progseg&e=545754873&seg=3&siteplayer=true&dl=1 August 24, 2017·6:11 PM ET Heard on All Things Considered Michaeleen Doucleff 2016 square Michaeleen Doucleff Twitter The words "endangered species" often conjure up images of big exotic creatures. Think elephants, leopards and polar bears.
But there's another of type of extinction that may be occurring, right now, inside our bodies.
Yes, I'm talking about the microbiome — that collection of bacteria in our intestines that influences everything from metabolism and the immune system to moods and behavior.
For the past few years, scientists around the world have been accumulating evidence that the Western lifestyle is altering our microbiome. Some species of bacteria are even disappearing to undetectable levels.
"Over time we are losing valuable members of our community," says Justin Sonnenburg, a microbiologist at Stanford University, who has been studying the microbiome for more than a decade.
Now Sonnenburg and his team have evidence for why this microbial die-off is happening and what we can possibly do to reverse it.
The study — published Thursday in the journal Science — focuses on a group of hunter-gatherers in Tanzania, called Hadza.
Their diet consists almost entirely of food they find in the forest, including wild berries, fiber-rich tubers, honey and wild meat. They basically eat no processed food — or even food that comes from farms.
"They are a very special group of people," Sonnenburg says. "There are only about 2,200 left and really only about 200 that exclusively adhere to hunting and gathering."
Sonnenberg and his colleagues analyzed 350 stool samples from Hadza people taken over the course of about a year. They then compared the bacteria found in Hadza to those found in 17 other cultures around the world, including other hunter-gatherer communities in Venezuela and Peru and subsistence farmers in Malawi and Cameroon.
The findings were quite clear: The further away people's diets are from a Western diet, the greater the variety of microbes they tend to have in their guts. And that includes bacteria that are missing from American guts.
"So whether it's people in Africa, Papua New Guinea or South America, communities that live a traditional lifestyle have common gut microbes — ones that we all lack in the industrialized world," Sonnenburg says.
In a way, the Western diet — that's low in fiber and high in refined sugars — is basically wiping out species of bacteria from our intestines.
That's the conclusion Sonnenburg and his team reached after analyzing the Hadza microbiome at one stage of the yearlong study. But when they checked several months later, they uncovered a surprising twist: The composition of the microbiome fluctuated over time, depending on the season and what people were eating. And at one point, the composition started to look surprisingly similar to that of Westerners' microbiome.
During the dry season, Hadza eat a lot of more meat — kind of like Westerners do. And their microbiome shifted as their diet changed. Some of the bacterial species that had been prevalent disappeared to undetectable levels, similar to what's been observed in Westerners' guts.
But then in wet season — when Hadza eat more berries and honey — these missing microbes returned although they're not really sure what's in these foods that bring the microbes back.
"I think this finding is really exciting," says Lawrence David, who studies the microbiome at Duke University. "It suggests the shifts in the microbiome seen in industrialized nations might not be permanent — that they might be reversible by changes in people's diets.
"The finding supports the idea that the microbiomes is plastic, depending on diet," David adds.
Now the big question is: What's the key dietary change that could bring the missing microbes back?
Lawrence thinks it could be cutting down on fat. "At a high level, it sounds like that," he says, "because what changed in the Hadza's diet was whether or not they were hunting versus foraging for berries or honey," he says.
But Sonnenburg is placing his bets on another dietary component: fiber — which is a vital food for the microbiome.
"We're beginning to realize that people who eat more dietary fiber are actually feeding their gut microbiome," Sonnenburg says.
Hadza consume a huge amount of fiber because throughout the year, they eat fiber-rich tubers and fruit from baobab trees. These staples give them about 100 to 150 grams of fiber each day. That's equivalent to the fiber in 50 bowels of Cheerios — and 10 times more than many Americans eat.
"Over the past few years, we've come to realize how important this gut community is for our health, and yet we're eating a low-fiber diet that totally neglects them," he says. "So we're essentially starving our microbial selves."
Web Resources
fiber www.npr.org/tags/243939819/fiber Hadza www.npr.org/tags/191340563/hadza microbiome www.npr.org/tags/172709084/microbiome
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Post by the Scribe on Aug 25, 2017 5:10:04 GMT -5
Gut Bacteria Balance and Your Health! Immunology in the Gut Mucosa The human microbiome and what we do to it Published on May 31, 2012 Did you know that you and I are only 1% human — we've 90 trillion cells which don't belong to us. Yes we are more bacteria than human. Have you ever wondered what it means to be human? It turns out that only a tiny percentage of what you and I are made of is actually human — and we need our non-human bits to survive. This part of us now has a name — it's called our microbiome. But we're doing dreadful things to this hidden majority and it's damaging our health as a result. From the Tonic series produced with the assistance of NPS. For more information visit: www.nps.org.au 10 Signs and Symptoms that You Have an Unhealthy Gut (leaky gut) Probiotics specifically for chronic diseases like Alzheimer's are popping up. I had read that studies showed that people who took antibiotics that killed off gut bacteria actually delayed the onset of Alzheimer's but now it seems that there may be certain gut bacteria that are needed specifically for that disease and most likely other diseases like Parkinson's as well.Here is one such probiotic: www.endomune.com/about/ (but do your research before deciding which to purchase as many have been tested for efficacy and they are not all created equal)
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Post by the Scribe on Sept 13, 2017 14:23:14 GMT -5
I had a friend, a fellow animal rescue volunteer that found himself in the hospital, close to death with c-diff. Nothing was working until they tried an experimental type of therapy called "fecal transplant." It worked! It is also being used on animals with c diff.
As pointed out before studies are looking to other auto immune diseases being caused by micro biome challenges including Autism, Alzheimer's and Parkinson's. The evidence for this is mounting.
Earlier I had thought that just taking probiotics would help but as I research this I find there are certain probiotics that will help while others not. And NOT all probiotic manufacturers are created equal. You have to do your research on this one.
Studies Show Link Between Multiple Sclerosis And Gut BacteriaPlay 05:37 : www.wbur.org/hereandnow/2017/09/13/studies-multiple-sclerosis-gut-bacteria September 13, 2017
Two recent studies have found strong evidence that intestinal bacteria play a role in multiple sclerosis, an incurable autoimmune disease. The studies advance our understanding of how the microbiome is linked to multiple sclerosis and what potential treatments or prevention methods might be developed for the disease.
Here & Now's Meghna Chakrabarti talks with Sharon Begley (@sxbegle) of our partners at STAT about what the findings mean.
This segment aired on September 13, 2017.
www.wbur.org/hereandnow/2017/09/13/studies-multiple-sclerosis-gut-bacteria
Gut germs play role in multiple sclerosis, studies show. Are probiotics for MS next? By Sharon Begley @sxbegle
/September 11, 2017 Two teams of scientists have found the strongest evidence yet that intestinal bacteria play a role in multiple sclerosis, an incurable disease in which the body’s immune system attacks the myelin coating on neurons, causing tremors, fatigue, cognitive problems, and more.
Gut germs that were unusually abundant in people with MS changed white blood cells in a way that made them more likely to attack the body’s own cells, including neurons, one study reported on Monday; the other experiment found that gut germs from people with MS made mice more likely to develop the disease than did gut germs from their identical but healthy twins.
You’ll want to know:
Although it might seem crazy that gut bacteria could affect neurons, evidence for that has been steadily accumulating, so much so that an international consortium is devoted to understanding which microbes protect against or promote MS.
The new studies strengthen the case for an MS-microbiome link.
Is the gut microbiome an important cause of obesity?
In one, scientists led by Sergio Baranzini of the University of California, San Francisco, analyzed the microbiomes of 71 MS patients and 71 healthy people. Bacteria called Acinetobacter and Akkermansia were very rare in healthy people but more abundant in the MS patients.
That was in line with earlier studies finding, for instance, that people with one form of MS have different gut bacteria than healthy people. But the earlier work didn’t show whether having MS changes the gut microbiome or vice versa. The UCSF team therefore took the next step, running what Baranzini called “the most stringent test of causality.”
They put Acinetobacter and Akkermansia bacteria into samples of healthy blood. The microbes increased the kind of cells that activate immune attack (they’re called T helper cells) and decreased the kind (regulatory T cells) that suppress excessive immune responses, including autoimmune attacks as in MS.
There was another intriguing connection: at least one species of Acinetobacter has molecules on its surface that mimic myelin, the nerve cell coating that the immune system attacks in MS. That suggests the bacteria might trigger immune attacks that hit myelin, too, as when soldiers who inadvertently resemble the enemy get hit by friendly fire. The discoveries, the UCSF team wrote in Proceedings of the National Academy of Sciences, suggest “a previously unknown environmental contributor to MS.”
In the second study, scientists led by Hartmut Wekerle of Germany’s Max Planck Institute of Neurobiology examined 34 pairs of twins in which only one of each had MS. Transplanting gut microbes from the twins into lab mice that develop MS, they found that more of the mice receiving the MS microbiome developed a mouse version of MS than did mice receiving transplants from the healthy twin.
Why it matters:
If the results are right, and if certain gut bacteria are necessary for MS, they could serve as the basis for microbiome-based therapy or even prevention of the disease. Much as fecal transplants from healthy donors treat life-threatening infections of the bacterium C. difficile, so they might be used to treat MS — or, if given before someone with a genetic risk develops MS, prevent it.
Alternatively, probiotics that preferentially nourish bacteria that compete with the MS-causing kinds might keep the latter in check, Baranzini said, though he cautioned that probiotics have not yet been shown to cause the wholesale microbiome changes that might be needed to prevent or cure disease.
What they’re saying:
Scientists not involved in the new studies used phrases such as “unique insights” and “major advance” to describe the results. Together, the experiments show that bacteria in the guts of people with MS promote disease-causing immune activity, said immunologist Francisco Quintana, of the Ann Romney Center for Neurologic Diseases at Brigham and Women’s Hospital in Boston, who said these were “landmark papers.” Ashutosh Mangalam, of the University of Iowa Carver College of Medicine, who led a 2016 study finding that people with MS have a microbiome different from healthy people’s, was more cautious, however. Because both of the new studies transplanted the entire community of gut bacteria from people into mice, they couldn’t show which particular bugs played necessary or sufficient roles in MS.
Read More
Q&A: What if we could take control of our changing microbiomes?
But keep in mind:
The explosion of microbiome research has led to inflated claims. It’s too soon to know how important the microbiome is in increasing the risk of MS compared to the 200 genetic variants that have been linked to the disease, or compared to the Epstein-Barr virus, smoking, and low levels of vitamin D, which also seem to play a role. Even the new studies clashed somewhat: Unlike the UCSF study, the German research found no major differences between the overall microbiomes of twins with and without MS. Finally, mouse models of MS are not perfect analogues of the human disease, and mouse immune systems aren’t identical to people’s.
The bottom line:
Together, the two studies advance the idea that gut microbes play a role in turning the immune system against nerve cells, causing MS. It will take a lot more work to develop cures or preventive strategies based on that, but the research raises the intriguing possibility of treating an often-devastating disease with something as low-tech as fecal transplants or probiotics.
About the Author Sharon Begley Senior Writer, Science and Discovery Sharon covers science and discovery. sharon.begley@statnews.com @sxbegle www.statnews.com/2017/09/11/gut-microbiome-multiple-sclerosis/
More From Other Publishers
Multiple sclerosis: What role do gut microbes play? Medical News Today
Of bugs and brains: Gut bacteria affect multiple sclerosis California Institute of Technology, ScienceDaily, 2010
Loss of microbial gut diversity a threat to health? Medical News Today
Changes uncovered in the gut bacteria of patients with multiple sclerosis Brigham and Women's Hospital, ScienceDaily, 2016
Gut microbes at root of severe malnutrition in kids Washington University School of Medicine, ScienceDaily, 2013
Wound-healing intestinal bacteria: Like shrubs after a forest fire Emory Health Sciences, ScienceDaily, 2016
Connections between gut microbiota and the brain European Academy of Neurology, ScienceDaily, 2016
Healthy diet discourages obesity microbes in gut Catharine Paddock PhD, Medical News Today, 2013
Gut microbes influence colon cancer risk Catharine Paddock PhD, Medical News Today, 2013
Gut bacteria and the brain: Are we controlled by microbes? Tim Newman, Medical News Today
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Post by the Scribe on Oct 3, 2017 19:10:39 GMT -5
Above is the first line of the article's body. I see it differently:
Atrophy of the brain causes Alzheimer's.
And how and why does this atrophy occur? ans. America's war on cholesterol.Parkinson's, Alzheimer's and Multiple Sclerosis have many things and causes in common. When certain immune responses happen or don't happen in one's body then one of these ailments may raise it's ugly head. That is why this study may be very important to all 3 of these diseases. I also find that sleeping disorders are very common with all 3. We know Linda has long suffered with sleep apnea so people with that problem take heed in this study.
My own research is finding that eating eggs (over easy where the yolks are runny) is FOOD FOR THE BRAIN. The brain is made up of cholesterol and cholesterol lowering drugs (like statins) are causing so many problems. The anti egg campaign of old is also a factor. Eggs are your friend.Brain's Link To Immune System Might Help Explain Alzheimer'sOctober 3, 2017·4:55 PM ET Heard on All Things Considered
Listen: ondemand.npr.org/anon.npr-mp3/npr/atc/2017/10/20171003_atc_brains_link_to_immune_system_might_help_explain_alzheimers.mp3?orgId=1&topicId=1128&d=229&p=2&story=555353033&t=progseg&e=555295128&seg=18&siteplayer=true&dl=1
Alzheimer's disease causes atrophy of brain tissue. The discovery that lymph vessels near the brain's surface help remove waste suggests glitches in the lymph system might be involved in Alzheimer's and a variety of other brain diseases. Alfred Pasieka/Science Source
www.npr.org/sections/health-shots/2017/10/03/555353033/brains-link-to-immune-system-might-help-explain-alzheimers
Fresh evidence that the body's immune system interacts directly with the brain could lead to a new understanding of diseases from multiple sclerosis to Alzheimer's.
A study of human and monkey brains found lymphatic vessels — a key part of the body's immune system — in a membrane that surrounds the brain and nervous system, a team reported Tuesday in the online journal eLife.
Lymphatic vessels are a part of the lymphatic system, which extends throughout the body much like our network of veins and arteries. Instead of carrying blood, though, these vessels carry a clear fluid called lymph, which contains both immune cells and waste products.
The new finding bolsters recent evidence in rodents that the brain interacts with the body's lymphatic system to help fend off diseases and remove waste. Until a few years ago, scientists believed that the brain's immune and waste removal systems operated independently.
The discovery of lymphatic vessels near the surface of the brain could lead to a better understanding of multiple sclerosis, which seems to be triggered by a glitch in the immune system, says Dr. Daniel Reich, an author of the study and a senior investigator at the National Institute of Neurological Disorders and Stroke.
"How the immune system interacts with the brain is fundamental to how multiple sclerosis develops and how we treat multiple sclerosis," Reich says.
There's An Amazing New Drug For Multiple Sclerosis. Should I Try It?
Current treatments for multiple sclerosis often involve drugs that suppress the immune system.
The research also has implications for diseases like Parkinson's and Alzheimer's.
These diseases occur as certain toxic waste products accumulate in the brain. And lymphatic vessels appear to be part of the system that usually removes these waste products.
"The discovery of a lymphatic system in the brain raises the possibility that a disorder of the lymphatic system is somehow involved in the causation of Alzheimer's disease," says Dr. Michael Weiner, a professor of radiology at the University of California San Francisco, who was not connected with the study.
That sort of thinking is a radical change from just a few years ago, Reich says.
For centuries, most scientists believed that the body's lymphatic system didn't connect to the brain, Reich says. "The brain is thought to be what is called immune-privileged," he says. "It has a different immune system from the rest of the body."
So Reich was intrigued when he heard a talk in 2015 by Jonathan Kipnis, who directs the neuroscience department at the University of Virginia.
"He showed very clearly in this talk that there are lymph vessels in the head, which I had learned in medical school didn't exist," Reich says.
But the evidence was in mice. So Reich and a team of scientists used MRI to study the brains of several human volunteers.
Where Does Alzheimer's Treatment Go From Here? The scientists injected a special dye into the bloodstream, then watched to see where it went. They focused on the dura mater, the outermost membrane that protects the brain and nervous system.
As expected, the team saw some of the dye leak out of blood vessels in the dura mater. But then they could see that the leaked dye was being collected by different vessels – which is exactly what happens in the lymphatic system.
"That gave us some evidence that there are vessels here that are behaving different from blood vessels," Reich says. "But we weren't sure that they were lymphatic vessels."
To be certain, Reich's team spent years perfecting a technique to reveal the lymphatic vessels in the dura mater of brains taken from human cadavers. This allowed the scientists to confirm the presence of these vessels near the surface of the brain. And it strongly suggested that the lymphatic system interacts directly with the brain.
The results extend the findings of a landmark study published in 2013. It found that the brain appears to flush out waste products during sleep.
But it wasn't clear how these waste products were draining out of the head. Now it appears that at least some of the waste might be exiting through the lymphatic system.
Brains Sweep Themselves Clean Of Toxins During Sleep www.npr.org/sections/health-shots/2013/10/18/236211811/brains-sweep-themselves-clean-of-toxins-during-sleep
Lack Of Deep Sleep May Set The Stage For Alzheimer's www.npr.org/sections/health-shots/2016/01/04/460620606/lack-of-deep-sleep-may-set-the-stage-for-alzheimers
Dementia can be reversed naturally kateswaffer.com/2013/02/09/dementia-can-be-reversed-naturally/
Want a healthy brain? Have eggs for breakfast (and don't worry, they won't cause dementia) www.dailymail.co.uk/health/article-4108906/Want-healthy-brain-eggs-breakfast-don-t-worry-won-t-cause-dementia.html
Five Types Of Dementia - Dr. Joel Wallach Causes: Parkinson's Disease - ALS - Alzheimer's Disease - MS - Dementia
From Dr. Joel Wallach 10-5-17 regarding a Parkinson's call and his latest protocol to use for it on a coasttocoastam radio show:
PARKINSONS IS A DEFICIENCY OF THE WHITE MATTER OF THE BRAIN TAKE: 2EA “HEALTHY BRAIN AND HEART PACK” “SYNAPITVIE” 2EA A DAY 6 EGGS TWICE A DAY....SOFT OR RUNNY YOLK “GOOD HERBS” BRAIN SUPPORT (YOUNGEVITY PRODUCTS)
STAY AWAY FROM BAD STUFF I.E. GLUTEN, FRIED FOODS, VEGETABLE OILS, ETC.
EAT HIGH FATTY CHEESES like BRIE. STICK OF BUTTER PER DAY 1/3 STICK EACH MEAL OR PUT IN YOUR COFFEE INSTEAD OF CREAM
GREEK YOUGURT WITH BERRYS AND HEAVY CREAM EAT/DRINK WHOLE FAT MILK AND CHEESE AND NOT THE 1% STUFF OR NON-FAT.
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Post by Ruth on Oct 5, 2017 12:58:33 GMT -5
Whoa. I just watched the headlines shown in this first posted video on this thread from many prestigious publications regarding the link between Parkinson's and other neurological diseases and cholesterol reducing drugs. There must be something to this.
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